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Define inter-occasion variability (IOV) into the dataset. A new variable of name 'colname' will be output into the dataset and will vary at each dose number according to the given distribution.

Source: R/treatment_iov.R
IOV.Rd

Define inter-occasion variability (IOV) into the dataset. A new variable of name 'colname' will be output into the dataset and will vary at each dose number according to the given distribution.

Usage

IOV(colname, distribution = NULL, dose_numbers = NULL, omega_ref = NULL)

Arguments

colname

name of the column that will be output in dataset

distribution

distribution

dose_numbers

dose numbers, if provided, IOV is generated at these doses only. By default, IOV is generated for all doses.

omega_ref

name of the OMEGA (e.g. 'IOV' without the 'OMEGA_')

Value

an IOV object